Neuroblastoma Survival has Improved 05/11/2010
Between 1979 and 2005, ten-year overall survival with neuroblastoma improved from 34.9% to 65%. The results of this study, conducted in Italy, were published in the Journal of Clinical Oncology. Neuroblastoma is a disease in which cancerous cells form in the nerve tissues of the adrenal gland, neck, ...

Immunotherapy Improves Outcomes for Patients with High-risk Neuroblastoma 05/21/2009
According to the results of a Phase III clinical trial that will be presented at the 2009 annual meeting of the American Society of Clinical Oncology (ASCO), use of an investigational immunotherapy treatment reduced the risk of relapse and improved survival among patients with high-risk neuroblastoma. Neuroblastoma is a disease in ...

Good Prognosis for Neuroblastoma Patients Diagnosed Before 18 Months of Age 09/20/2005
According to three studies published together in the Journal of Clinical Oncology, children between the ages of 12 and 18 months have a good prognosis after treatment for disseminated neuroblastoma. As well, they may not require the intensive treatment currently recommended for children over 12 months of age. Neuroblastoma is ...

Chemotherapy and Autologous Stem Cell Transplant Improve Outcome for Children with Neuroblastoma 08/23/2005
Children and adolescents with high-risk neuroblastoma have better outcomes after treatment with high-dose chemotherapy and autologous stem-cell transplant than after oral maintenance chemotherapy, according to the results of a clinical trial published in the journal Lancet Oncology. Neuroblastoma is a disease in which cancerous cells form in the nerve tissues ...

Chromosomal Changes May Help Predict Pediatric Neuroblastoma Outcomes 05/20/2005
Researchers affiliated with the Children's Oncology group recently reported that changes associated with chromosome 11q are a strong predictor of poor prognosis in patients with pediatric neuroblastoma. These results were recently presented at the 2005 annual meeting of the American Society of Clinical Oncology. Neuroblastoma is a disease in which ...

Vitamin Supplementation During Pregnancy Decreases Incidence of Neuroblastoma in Children 08/28/2002
According to a recent article in the journal Epidemiology, women who supplement with daily vitamins and minerals during their pregnancy significantly reduced the risk of their children developing neuroblastoma. Neuroblastoma is a rare cancer of the tissues that form the sympathetic nervous system. The sympathetic nervous system is the ...

Screening for Neuroblastoma Does Not Appear to Reduce Mortality 04/29/2002
According to recent articles published in The New England Journal of Medicine, general screening of infants and toddlers for neuroblastoma does not appear to reduce mortality caused by the disease. Neuroblastoma is a rare cancer of the tissues that form the sympathetic nervous system. The sympathetic nervous system is ...

F38 and GM-CSF Produce Anti-Cancer Responses in Patients with Non-Progressive Neuroblastoma 02/14/2002
A recent article published in the Journal of Clinical Oncology suggests that the combination of F38, a monoclonal antibody, and GM-CSF, an immune cell growth stimulator, produce anti-cancer responses in patients with neuroblastoma that is stable, but only minimally responsive to standard therapy. Neuroblastoma is a rare cancer of ...

New Blood Test May Help Determine Treatment Options for Neuroblastoma 02/14/2002
A new blood test for patients diagnosed with neuroblastoma may help determine which patients are at the greatest risk for a cancer recurrence. This could help to more appropriately define initial treatment regimens, according to a recent article published in the Journal of Clinical Oncology. Neuroblastoma is a ...

New Monoclonal Antibody Appears Promising for Treatment of Neuroblastoma 02/14/2002
A novel monoclonal antibody, called ch14.18, has shown promising results in the initial phases of clinical trials for the treatment of patients with neuroblastoma, according to a recent article published in the Journal of Clinical Oncology. Neuroblastoma is a rare cancer of the tissues that form the sympathetic nervous ...

Surgery Alone Remains Primary Treatment for Stage I and II Neuroblastoma 02/14/2002
Neuroblastoma is a type of cancerous tumor that can occur in children, most often in those younger than 2 years old. This cancer can affect the chest, abdomen, adrenal gland or neck, and in some cases there is extension of the cancer to the spine. Depending on the ...

High-Dose Chemotherapy and Bone Marrow Transplantation is Superior Therapy for Children with High-Risk Neuroblastoma 02/14/2002
Children with high-risk neuroblastoma have a long-term survival rate of only 15% with currently available standard treatment options. Patients at high risk of failure following standard treatment include those with widespread cancer and those with an aggressive histology. Early clinical studies evaluating high-dose chemotherapy with blood or bone ...